Fulham v Wolves line-ups: Christensen plays, Wolves midfielder out

first_imgFulham boss Kit Symons named a strong, attacking side for the FA Cup third-round clash with Wolves, who are without suspended midfielder Kevin McDonald.Whites midfielder Lasse Vigen Christensen has made a quicker than expected recovery from a hamstring problem and is named in the starting line-up. Fulham:  Bettinelli; Grimmer, Hutchinson, Bodurov, Stafylidis; Parker; Christensen, Fofana; McCormack; Rodallega, Woodrow.Subs: Kiraly, Burn, Kavanagh, Roberts, Ruiz, Williams, Dembélé. Wolves:  Ikeme; Iorfa, Batth, Stearman, Doherty; Evans, Price, Henry, Edwards, Sako; Clarke.Subs: Kuszczak, Saville, Ricketts, McAlinden, Ebanks-Landell, Jacobs, Dicko.Follow West London Sport on TwitterFind us on Facebooklast_img read more

Warriors-Jazz cheatsheet: Utah looking to take season series over the champs

first_imgOAKLAND – With the All-Star break on the horizon, the Warriors will try win to win their fifth straight game, while the Jazz, who are in the midst of their own mid-season run, will try to ruin the champs’ good vibes Tuesday night.Here’s everything you need to know about the matchup.When/Where: Oracle Arena, 7:30 p.m (NBCSBA)Jazz projected starting lineup: Derrick Favors, Joe Ingles, Rudy Gobert, Ricky Rubio, Donovan Mitchell Jazz Stock Report: Since the last matchup between these …last_img read more

Alex Smith’s wife celebrates ex-49er’s recovery from ghastly leg injury in emotional Instagram post

first_imgRemember when life was simple for Alexander Douglas Smith? All he had to worry about was the notoriety of being taken with the first pick in the 2005 NFL draft by a 49ers team in the midst of eight consecutive losing seasons. And being paired with novice head coach Mike Nolan whose expertise lay on the defensive side of the ball. And then being passed off to Mike Singletary, another head coaching novice whose expertise consisted of knocking quarterbacks down, not building them up.Related …last_img read more

Stem Cell Science Can Proceed Ethically

first_img(Visited 20 times, 1 visits today)FacebookTwitterPinterestSave分享0 With adult and induced pluripotent stem cells in abundance, it should not be necessary to destroy human embryos to understand stem cell science.Research with adult stem cells and induced pluripotent stem cells (iPSC) is continuing to produce amazing discoveries.Self-healing heart:  The heart has a store of stem cells that is capable of natural regenerative capacity, scientists at Kings College London found (Medical Xpress), promising new treatment for heart failure:The study, published today in the journal Cell, shows that if the stem cells are eliminated, the heart is unable to repair after damage. If the cardiac stem cells are replaced the heart repairs itself, leading to complete cellular, anatomical and functional heart recovery, with the heart returning to normal and pumping at a regular rate.Also, if the cardiac stem cells are removed and re-injected, they naturally ‘home’ to and repair the damaged heart, a discovery that could lead to less-invasive treatments and even early prevention of heart failure in the future.Reprogramming iPSC mutations:  For patients with a blood disease, researchers at Children’s Hospital of Philadelphia found they could take skin cells, create iPSCs from them, fix the mutation that causes the blood disease, re-inject them, and cure the disease (Science Daily).  “The technology for generating these cells has been moving very quickly,” the hematologist said.Bad teeth?  Urine luck:  Science Daily reported a “number one source” for new teeth: stem cells in a patient’s own urine.  There’s potential in that liquid that is flushed down the drain to regenerate iPSCs that can be coaxed into creating hard parts of teeth structures.  “The system mimics normal tooth development, which results from an interaction between two different cell types; epithelial cells, which give rise to enamel, and mesenchymal cells, which give rise to the other three main components of teeth (dentin, cementum and pulp).”  iPSC technology is good news, because “their derivation avoids the controversial use of embryos” and the cells are not rejected by the patient.Functional blood vessels:  Scientists at Harvard and Massachusetts General Hospital succeeded in growing functional blood vesses in vivo from iPSCs, Medical Xpress reported with the headline, “Patient, heal thyself.”  By overcoming several challenges with the method, they have shown that it is no longer necessary to rely on human embryonic stem cells to do the job.   According to a researcher, “the use of vascular precursors from human embryonic stem cells pose ethical and immunological concerns that are averted with the use of iPS-derived vasculogenic cells.”Understanding adult stem cells:  European scientists are learning how stem cells in human skin differentiate, according to Science Daily.  By making proteins “shine,” they can monitor the developmental pathways as the stem cells form different tissues and organs in the skin, such as sweat glands, fat, or hair follicles.  They found that the cells do not follow a simple hierarchy from primitive stem cell to finished tissue, but “there are differentiated levels of stem cells and that it is their close micro-environment that determines” the tissue generated.  These findings will help regenerative medicine avoid “waking up” cells in the wrong place or time that might result in cancer.Understanding embryonic stem cells:  Scientists are trying to understand the expression of embryonic stem cells – in mice.  Science Daily explored the paradox of how these cells can be marked with “on” and “off” regulatory marks simultaneously, like seeing a red and green light at the same time.  A more “nuanced” view of the genetic code is showing a method in the paradox: stem cells can be maintained in a “bivalent state” that allows them to go down either path, depending on context.Understanding the differences:  By studying the substances in zebrafish cells that can convert body cells back to stem cells through a kind of “eraser” that removes the body cell’s memory of what it was, scientists are finding out how to make induced stem cells resemble embryonic cells more closely, Science Daily reported.  And why is this good?  “These multi-talented cells are the focus of much attention in biomedical research because experts hope to use them to regenerate damaged organs without having to resort to embryonic stem cells.”Learning from flatworms:  Flatworms (planaria) have an uncanny ability to regenerate their heads (students sometimes create two-headed planaria in science lab).  At MIT, Medical Xpress reported, scientists made the discovery that muscle cells in the flatworm have the ability to communicate with their nearby stem cells, informing them what kind of tissue is needed.  Certain “position control genes,” which are “highly conserved and many are found in other animals, including humans,” are controlled by particular proteins in the muscle cells.  When wounded, cells alter these proteins to control which PCGs are made, signaling pathways that direct the stem cells to know what kinds of repairs are needed.  “Because the muscle fibers are long, when you cut the animal, it can immediately respond by contracting to close the wound, turning on wound-induced genes at that site, and eventually changing the pattern of expression to respond to the missing tissue.”  Understanding that flow of information “opens whole new areas of research,” the article said.It was just in time.  In 2007, when Japanese scientists learned how to create iPSCs from adult tissues (a Nobel prize discovery), they took the wind out of embryonic stem cell research.  Throughout the Bush and early Obama administrations, scientists were clamoring for rights to destroy human embryos in order to understand stem cells, pulling at the public’s heartstrings to claim patients were dying without them, because conservatives didn’t care about people.  Now that iPSCs and adult stem cells are plentiful and just as effective, why use ESCs at all?  Researchers can learn all they need to know about them from mice and zebrafish.  A subtext we hope you noticed in these stories is that many scientists today would prefer to avoid the ethical controversies.  They want to help patients “without having to resort to embryonic stem cells.”  That’s a welcome change of heart.The miracle cures possible with adult stem cells and iPSCs are at the doorstep.  We have much to look forward to: new hearts, new teeth, new blood vessels and much more.  This will be healthy, morally good, practical research that has nothing to do with evolution.  We need more of that kind of science.last_img read more

South African eco-lodges on A-list

first_img17 March 2009Three South African lodges are included on the latest National Geographic Adventure magazine list of 50 top eco-lodges. Phinda Private Game Reserve, Tswalu Kalahari Reserve and Bushmans Kloof Wilderness Reserve have taken their place among the top environmentally friendly tourism destinations in the world.Of the 50 establishments recognised as the most earth-friendly, 17 are in Africa. Four are in Kenya, with two each in Namibia, Botswana and Tanzania, and one each in Mozambique, Seychelles, Egypt and Morocco.MediaClubSouthAfricaFree high-resolution photos and professional feature articles from Brand South Africa’s media service. National Geographic Adventure says that a decade ago the number of true eco-lodges on the planet could be counted on two hands. But no longer are they solely found deep in the African bush or Central American jungle, as these are not the only eco-systems that need nurturing. Today, ecolodges are found in a diversity of landscapes and locales, ranging from island and savannah to mountain and desert terrain.As far back as 1990 the Ecotourism Society defined eco-tourism as “responsible travel to natural areas that conserves the environment and improves the well-being of local people’.And an eco-lodge, according to the Ecotravel Center, a division of the non-profit Conservation International Foundation, can be defined as a nature-dependent tourist lodge that meets the philosophy and principles of ecotourism.Ecolodges, therefore, are those establishments that focus strongly on a greener way of operating, including the support of local communities, the creation of far-reaching conservation initiatives, and a firm emphasis on adventure. Oh, and guests can expect dazzling locations and unsurpassed service and comfort too.A good eco-lodge should engage in responsible practices such as paying respect to local traditions by incorporating cultural elements into the design and decor, disrupting the natural environment as little as possible and using local plant life as much as possible, sourcing food from local farmers, using recycled or recyclable materials in building, and bridging cultural gaps by promoting cultural exchanges.Eco-lodges are becoming increasingly fashionable, not only because many of them genuinely deserve their place among the world’s top destinations, but also because more tourists are listening to their consciences and actively supporting the vital role that eco-lodges play in conservation. These fine citizens of the earth will return home knowing that their holiday contributed to preserving the world’s natural environment.In South Africa, the three establishments that have been singled out by National Geographic Adventure magazine have shown firm commitment to those eco-tourism principles.Tswalu Kalahari ReserveThe Tswalu Kalahari Reserve is the creation of the late Manchester entrepreneur Stephen Boler, who was at one time the largest single shareholder in Manchester City football club. Over a period of four years Boler bought 34 farms in the Kalahari Desert and combined them to form a vast 1 000km² game reserve. Since 1999 Tswalu, the largest private reserve in South Africa, has been owned by the Oppenheimer mining dynasty.Tswalu has won a number of international awards, including several AA Travel Guide accolades and a Conde Nast Traveler 2007 World Savers Award. While it offers a superb safari experience, its primary aim is conservation and socio-economic development in the region. Its architectural designs minimise water and energy usage while extensive use of solar energy and everyday waste recycling substantially reduce the impact on the environment.Tswalu is committed to restoring and preserving the natural environment and ecological processes that are unique to the Kalahari ecosystems, thereby providing a sanctuary for endangered species such as the African wild dog, listed on the International Union for Conservation of Nature’s Red List.Some of Tswalu’s projects include a study of the mammals in the reserve and identification of their ecological roles, research into predator-prey relationships of the Kalahari lion in the reserve, a determination of the density of black rhino that can be sustained by vegetation in Tswalu, the development of a Tswalu spider database, and mapping the breeding success of raptors in the reserve.Phinda Private Game ReserveThe acclaimed Phinda Private Game Reserve in northern KwaZulu-Natal is a flagship establishment of &Beyond, previously known as Conservation Corporation or CC Africa. Phinda encompasses seven separate eco-systems ranging from woodland, grassland, wetland and forest, to mountain ranges, rivercourses, marshes and pans. The reserve is also home to a contingent of rare black rhino.Many of Phinda’s rangers and guides are drawn from the surrounding communities and are thus able to share a wealth of cultural information with guests. All are deeply committed to their work. The reserve runs a full-time ranger school, where prospective rangers study for eight weeks before joining a team and gaining more knowledge in the field.Phinda has embarked on a number of other important conservation and community projects, among them the establishment of a worm farm and organic garden in a nearby community, which will hopefully produce vegetables for purchase by the lodge, a black rhino range expansion project, the ongoing clearing of an invasive alien plant species known as Triffid Weed, an initiative to re-introduce lion into the reserve, and research into leopards in the area.Bushmans KloofSpectacular Bushmans Kloof Wilderness Reserve in the Western Cape, situated on the northern side of the Cederberg mountains about 270km north of Cape Town, boasts more than 130 rock art sites, some of which have been dated back to 10 000 years ago.The reserve was born in 1991 when the McAdam brothers bought seven farms and combined them to form the 75km² Bushmans Kloof. Initially the land was severely over-grazed and neglected, but the McAdams removed the livestock and let the land restore itself.Today, Bushmans Kloof shelters endangered species such as the Cape mountain zebra, the Cape clawless otter and the Clanwilliam yellow fish. Indigenous trees once more cover the land, which lies within the Cape Floral Kingdom, a proclaimed World Heritage site. The reserve has won much international acclaim, first in 2003 when the US-based magazine Travel and Leisure voted it as one of the world’s top 25 eco-lodges.Bushmans Kloof is a leading participant in the 1 600km² Agter-Pakhuis Conservancy project, which encourages farmers to employ ecotourism principles wherever possible. The reserve has also opened a heritage centre where photographs and artefacts, as well as traditional jewellery, musical instruments, hunting kits and more, pay homage to the culture of the Bushmen.First published by MediaClubSouthAfrica.com – get free high-resolution photos and professional feature articles from Brand South Africa’s media service.last_img read more

The Big Picture on Ultra-High-Def TV

first_imgA shift to the next generation of televisions known as Ultra-High-Definition (UHD), and sometimes 4K, could cost U.S. consumers an additional $1 billion annually unless further energy efficiency improvements are made, according to our new report.In fact, that energy waste could add up to an additional 8 terawatt-hours of electricity a year nationally — enough to power all the homes in San Francisco for three years. But the good news is that while UHD televisions use an average 30% more energy to operate than similarly sized high-definition (HD) televisions, that doesn’t have to be the case. Our new report shows that some of the best UHD models on the market today are dramatically more energy-efficient than the typical UHD television, using little to no more energy than the equivalent HD TV it would replace. Smart TVs are usually, but not always, so smartMost new televisions include internet connectivity which allows consumers to stream content from the web from applications like Netflix and YouTube without the need for a computer or supplemental device like Apple TV or a Roku box. While most of the Internet-connected televisions we tested had very low power levels (less than 1/2 watt in standby) and fast reboot times (below 10 seconds), some were much slower.Those TVs generally included a Quick Start feature, which if selected causes the television to transition much faster from standby to full power. Unfortunately, having this Quick Start feature enabled caused some models to use 20 to 30 watts of standby power even though the viewer had “turned off” the television. Unless absolutely necessary, consumers should avoid selecting Quick Start on your new television.It’s increasingly clear that UHD TV will likely be the dominant type of television sold in the next few years, and more bells and whistles are coming. To avoid an upsurge in television energy use and the related higher energy bills and power plant emissions that come from having to generate more electricity, we need TV manufacturers and their suppliers to continue to focus on improving the energy efficiency of their new TVs.And on the policy front we encourage:DOE to update its test method for measuring TV energy use to make sure the latest content and its potentially higher energy use is captured.EPA to reduce the size of the adder it provides for high resolution TVs in its next specification, Version 8.Utilities to offer rebates for the most energy efficient models.Regulators to consider setting minimum state or national energy efficiency standards to remove the least efficient new TVs from the market. RELATED ARTICLES Choosing an Energy-Efficient TelevisionVideo Gamers Could Save Billions in Energy CostsTackling the Plug Load ProblemChoosing an Energy-Efficient RefrigeratorAll About DishwashersAll About Washing MachinesAlternatives to Clothes Dryers Much to our surprise, about one in three televisions sold today has a screen 50 inches and greater. In general, energy use increases with larger screen sizes. One doesn’t have to look too far back to remember when 32 inches was considered a large television.During our analysis of manufacturer-reported energy use, we observed an almost three-fold range in the electricity consumption of similarly sized UHD televisions. This means that while there are some real energy hogs out there, with the worst consuming more electricity annually than a new mid-sized refrigerator, there are some really efficient models, too. The challenge is how to ensure the industry shifts toward the more efficient designs quickly before many of today’s 300 million televisions are replaced by UHD TVs. Settings really matterMost, but not all, of today’s new TVs come with a setting called Automatic Brightness Control (ABC) that automatically adjusts television screen brightness in response to changes in room light levels. From our laboratory testing of 50-inch to 55-inch televisions, we found that when enabled, ABC cuts energy consumption by a huge amount. On average, TVs with ABC off use 50% more electricity than when ABC is turned on.center_img Curiously, some manufacturers include ABC technology in their televisions, but choose not to ship their TVs with this feature enabled. (If they did, more would qualify for the highly coveted Energy Star label, indicating they are among the most energy-efficient models.) We recommend that consumers dig into the menu to look for, and select, the ABC feature to save money.The latest and greatest type of content that will be offered to viewers in the future is called High Dynamic Range (HDR), which promises more colors, brighter scenes, and blacker blacks. Prior to our study there was no published data on HDR’s incremental energy use. We obtained two movies produced in 4K HDR format and measured the power use during viewing on an UHD HDR television capable of playing it. On average, the HDR content on this TV caused the power use to increase on average by 47% compared to the 4K (non-HDR) version of the same movie.As shown in the accompanying graph (see Image #2, below), the power use during playback varied dramatically, spiking during the very bright scenes. We were only able to perform this test on one TV, so we can’t extrapolate the results to all HDR-capable televisions, but these findings should serve as a loud wake-up call and catalyst for additional measurements and updates to the U.S. Department of Energy’s (DOE) test method, which currently only uses HD content to determine television energy consumption. Noah Horowitz is a senior scientist in the energy program of the Natural Resources Defense Council, where he works on a wide range of energy efficiency issues. He holds a master’s degree in environmental engineering from Illinois Institute of Technology and a bachelor’s degree in chemical engineering from Carnegie-Mellon University. This post originally appeared at NRDC Switchboard. What exactly is UHD TV?The TV industry is heavily promoting its latest generation of televisions being marketed under the umbrella term UHD. These televisions provide higher resolution and in some cases a wider range of colors and enhanced contrast. Their higher resolution screens have at least 8 million pixels, which is four times greater than HD televisions, and are sometimes called 4K TVs. In order to fully benefit from the higher screen resolutions, a really big 4K TV is needed.last_img read more

Suspended constable dies in custody

first_imgA Manipur Police constable, suspended in connection with the escape of an extremist leader, has allegedly died in custody during questioning.Constable S.M. Manjur Ahmed was one of 10 police and medical personnel suspended after Thokchom Nando Singh of the outlawed Kangleipak Communist Party escaped while undergoing treatment at the Jawaharlal Nehru Institute of Medical Sciences in Imphal on March 25.Singh was arrested more than a decade ago for the kidnapping and murder of Lungnila Elizabeth, the eight-year-old daughter of former Minister Francis Ngajokpa in November 2003. “The constable was found dead in custody,” a police officer said, adding that they were trying to ascertain the reason for his death.last_img read more

Spurious liquor claims 10 lives in U.P.

first_imgTen people died after consuming spurious liquor in Uttar Pradesh’s Barabanki district on Tuesday, a spokesperson for Ajay Sahani, Superintendent of Police, said.A dozen officials of the Excise and the Police Departments have been suspended for the incident, officials said.The tragedy was reported from the Raniganj area under the Ramnagar police station of the district.Excise Minister J.P. Singh said six deaths had been confirmed so far. In the Home Department briefing held in the evening, IG Law and Order Praveen Kumar put the figure at 10 and said four others were critical.Among the victims were four members of one family. Several others had been admitted to the trauma centre in Lucknow.The district Excise officer and the superintendent along with the local Inspector, an SI and two police constables have been suspended, while the suspension of the circle officer was under process, said Mr. Kumar.The victims purchased the liquor from a local registered shop run by one Danvir Singh. A case has been lodged against him and two associates. While a salesman has been arrested, Singh is absconding.Minister J.P. Singh said it was a “lapse” on the part of the local officials that spurious liquor was sold at a licensed shop. “Somewhere it is a lapse of our officials and staff because there is a standing order that stock in every shop must be checked,” he said.Chief Minister Yogi Adityanath instructed the Principal Secretary, Excise Department, to probe the incident and take strict action against the culprits. The CM has directed a three-member committee led by the Excise commissioner to submit a report within 48 hours.The team would probe the source of the liquor, the accountability of the local Excise, police officials and any “conspiracy” angle, said Chief Secretary Anup Chandra Pandey.Rajeev Krishna, ADG Lucknow, said they were investigating at what stage the liquor was adulterated, whether at the factory or at the store. The shop did not have the licence to sell open liquor or serve it like a bar but could only sell closed bottles, he said.Mr. Adityanath announced an ex-gratia of ₹2 lakh each to the kin of the dead.last_img read more

Lokpal panel meets for last time tomorrow, differences persist

first_imgAs the joint drafting committee on Lokpal Bill winds up discussions on Tuesday, “serious differences” persisted between the government and civil society and fresh discord broke out over appointment and removal of the anti-corruption ombudsman.Both the sides will exchange their drafts version of the bill which will be merged into one document with differences listed for a final decision to be taken by the Union Cabinet, spokespersons for both the camps said.While HRD Minister Kapil Sibal, one of the official representatives on the committee, on Monday claimed that there was 80 to 85 per cent agreement between the two sides and that there was a “major breakthrough” and forward movement, the civil society side made light of the government claim.Sibal acknowledged that there was “strong divergence” of opinions but both the camps said the discussions were held in a “very cordial atmosphere”.The differences between the two sides remain on inclusion of Prime Minister within the ambit of the Bill as also the higher judiciary and conduct of MPs inside the House, funding model, CBI under Lokpal and Lokayuktas in state.At Monday’s meeting, an addition was made to this list when the two sides disagreed over who will constitute the panel to select Lokpal and who can approach the Supreme Court for removal.Arvind Kejriwal, a civil society member in the committee, said the government wanted the selection panel should have prime minister, Leaders of both the Houses in Parliament, Leaders of Opposition, Speaker, Cabinet Secretary, a Supreme Court judge and a High Court Chief Justice, which they say protects the existing corrupt system.advertisementKejriwal and other civil society representative Prashant Bhushan said the government maintained the Lokpal Bill would have a provision that it alone would have the provision to approach the Supreme Court for removal of the ombudsman and people would not have such a right.The government has so far agreed that the Prime Minister can be brought under the Lokpal only after he demits office and not when he is holding the office.Bhushan asked what is the logic of giving immunity to the Prime Minister when he is holding office because that will be the national security threat which he can compromise through corrupt deals.”None of us are hoping for an agreement tomorrow,” Kejriwal said adding both the sides will exchange drafts and one note containing differences will go to the Cabinet.On Sibal’s claim of 80-85 per cent agreement, Bhushan said the question is the quality of agreement. “All the basic principles are not of same importance. The differences are on the basic vision of the Lokpal which the civil society wants and which the government is prepared for,” he said.- With PTI inputsFor more news on India, click here.For more news on Business, click here.For more news on Movies, click here.For more news on Sports, click here.last_img read more