Cancer-killing cells made in the lab

first_img 217 Views   no discussions HealthLifestyle Cancer-killing cells made in the lab by: – October 27, 2014 Share A brain tumourBrain tumours are often solid and hard to reach so stem cells are an effective way of targeting themScientists from Harvard Medical School have discovered a way of turning stem cells into killing machines to fight brain cancer.In experiments on mice, the stem cells were genetically engineered to produce and secrete toxins which kill brain tumours, without killing normal cells or themselves.Researchers said the next stage was to test the procedure in humans.A stem cell expert said this was “the future” of cancer treatment.The study, published in the journal Stem Cells, was the work of scientists from Massachusetts General Hospital and the Harvard Stem Cell Institute.For many years, they had been researching a stem-cell-based therapy for cancer, which would kill only tumour cells and no others.They used genetic engineering to make stem cells that spewed out cancer-killing toxins, but, crucially, were also able to resist the effects of the poison they were producing.They also posed no risk to normal, healthy cells.In animal tests, the stem cells were surrounded in gel and placed at the site of the brain tumour after it had been removed.Their cancer cells then died as they had no defence against the toxins.Toxin-producing stem cells (in blue) help kill brain tumour cells in the tumour cavity (in green)Dr Khalid Shah, lead author and director of the molecular neurotherapy and imaging lab at Massachusetts General Hospital and Harvard Medical School, said the results were very positive.“After doing all of the molecular analysis and imaging to track the inhibition of protein synthesis within brain tumours, we do see the toxins kill the cancer cells.”He added: “Cancer-killing toxins have been used with great success in a variety of blood cancers, but they don’t work as well in solid tumours because the cancers aren’t as accessible and the toxins have a short half-life.”But genetically engineering stem cells has changed all that, he said.“Now, we have toxin-resistant stem cells that can make and release cancer-killing drugs.”Chris Mason, professor of regenerative medicine at University College London, said: “This is a clever study, which signals the beginning of the next wave of therapies.“It shows you can attack solid tumours by putting mini pharmacies inside the patient which deliver the toxic payload direct to the tumour.“Cells can do so much. This is the way the future is going to be.”Nell Barrie, senior science information manager for Cancer Research UK, said it was an “ingenious approach”.“We urgently need better treatments for brain tumours and this could help direct treatment to exactly where it’s needed.“But so far the technique has only been tested in mice and on cancer cells in the lab, so much more work will need to be done before we’ll know if it could help patients with brain tumours.”She said this type of research could help boost survival rates and bring much-needed progress for brain cancers.Dr Shah now plans to test the technique using a number of different therapies on mice with glioblastoma, the most common brain tumour in human adults.He hopes the therapies could be used in clinical trials within the next five years.BBC News Tweetcenter_img Share Sharing is caring! Sharelast_img read more

Dominican, Delroy Nesta Williams Featured in Inaugural Publication of US Magazine

first_imgEntertainmentInternationalLifestyleLocalNews Dominican, Delroy Nesta Williams Featured in Inaugural Publication of US Magazine by: – February 29, 2020 Share 180 Views   no discussions Share Sharing is caring!center_img Tweet Share Dominican writer, Delroy ‘Nesta’ Williams’ short story, The Ritual, is featured in the inaugural issue of US magazine, Gumbo.The magazine’s first publication, being launched in Chicago, USA on the last day of Black History Month (February 29th) is described as an ode to black life. It is a coffee table top book that is ideal for afrocentric individuals who aspire to attain contemporary art.Williams describes his choice as a contributing writer as a great opportunity especially given his humble beginnings as a writer.The magazine’s co-founder/creative director described The Ritual as “compelling, and an excellent fit with our vision for this inaugural issue.”Williams’ short story, selected from over 1000 submissions from over 400 creatives, delves into death and coming to terms with loss from the perspective of a young boy finding his space within a disjointed family.He mentioned that he is currently compiling a collection of poems entitled Moods and Attitudes and also working with other Dominican writers on a children’s book.He is also a contributor to a Dominican short story anthology entitled The Flying Crapaud which was recently published in 2020.Gumbo Magazine can be purchased online via the company’s website:GumboThe Flying Crapaud can be purchased online via Amazon.last_img read more

Liat to close offices in Dominica and Caribbean

first_img Share Share Share Tweet The efforts of the Waterfront and Allied Workers Union (WAWU) and other trade unions of the Caribbean, were not enough to persuade airline LIAT to change plans to close its ticketing offices around the region.The trade unions met with the board of directors of LIAT Tuesday in Barbados, to seek to talk Antigua-based carrier out of the proposal which could see 100 workers including those at the LIAT office in Dominica, lose their jobs.WAWU Secretary-Treasurer Kertist Augustus argued that unemployment levels in the region are already worrying.“In our response we looked at the whole question of the high unemployment which exists within the Caribbean and that we cannot accept these redundancies because to our mind they would further aggravate an already serious situation,” Augustus stated.He disclosed Wednesday the WAWU also spoke of sacrifices that LIAT workers have made in order to keep LIAT flying, including surviving suspension of pension payments at one point, as well as cut backs. Sharing is caring! LocalNewsRegional Liat to close offices in Dominica and Caribbean by: – March 30, 2011 But LIAT maintained that the cuts would save the company $3 million, at a time when it is grappling to survive in a tougher financial period.Tuesday’s meeting concluded that the closure of LIAT ticketing offices is inevitable.Trade unions are now focusing on ensuring LIAT workers receive fair deals. Augustus said LIAT intends on making the closure effective May 04 but the WAWU has argued this is too short notice.He said LIAT’s plan will have to change in the case of Dominica. “People whose services with LIAT is more than 10 years must be given the minimum of two months notice so the intention of LIAT to try to have early closure effective the 4th of May would have to be reviewed in the case of Dominica for some of the staff, to be effective the 4th of June.”Dominica Vibes News 44 Views   no discussionslast_img read more

DPSU awaits word from DOWASCO on intended job cuts.

first_img 240 Views   no discussions Sharing is caring! Share Tweet Sharecenter_img Share LocalNews DPSU awaits word from DOWASCO on intended job cuts. by: – May 7, 2011 General Secretary of the Public service union Thomas Letang says the union is still awaiting word from management of DOWASCO regarding its intended decision to cuts jobs and salary of some of its employees to deal with its financial problem.The company last month increased water rates by 15 percent, a move it believes will help the situation there.However Letang is still optimistic that the jobs and salaries of staff will be saved.“Since the interest in tariffs, DOWASCO has not officially indicated to us their position and what will happen. We told them what our concerns are and we thought that they would have contacted us already,” he said.Dominica Vibes Newslast_img read more

Jeans ferry service to make traveling easier throughout the Caribbean

first_img Share LocalNews Jeans ferry service to make traveling easier throughout the Caribbean by: – June 7, 2011 Sharing is caring! 211 Views   one comment Tweetcenter_img Share L’Express Des Iles has launced a new ferry service in an effort to meet the needs of their customers throughout the Caribbean.SAS Jeans which is expected to commence operation on 20th Octoberof this year with frequent services to Dominica, Guadeloupe, Martinique and St. Lucia all year round as opposed to L’Express Des Iles with very attractive fares.This new vessel was will consume less gas, less expensive to maintain, and less expensive to run which assists in the low fares which it will be introducing to the market. Mr. Boeme informed the press launch yesterday that although the price of gas has increased this will not affect Jeans unless the price per barel increases beyond US$100.Ian Douglas, Minister for Tourism expressed the delight of his ministry for this new service as he says it will eliminate some of the difficulties which visitors experience when coming in to the Nature Isle.“One of the key components of success to what we do is bringing people into Dominica, and brining people into Dominica means access. You will always hear us speak about access be it air access or sea access whatever means possible we can employ to bring people into Dominica because that is the measuring stick for those in the Tourism Industry….What we are doing here today is very important to us and we are very happy that you have decided to bring on this new ferry service Jeans.”Jeans will also offer weekend charters to Monsterrat, Antigua, St. Kitts & Nevis, St. Martin, and St. Vincent & the Grenadines and employ six Dominicans.Dominica Vibes News Sharelast_img read more

Three month training workshop for Diabetic foot officially launched in Dominica

first_imgHealthLifestyleLocalNews Three month training workshop for Diabetic foot officially launched in Dominica by: – June 10, 2011 Share Sharing is caring! 26 Views   no discussions Sharecenter_img Share Tweet Coordinator of the Health Promotion Resource Centre in the Ministry of Health Helen Royer says diabetes contributes greatly to the rate of mortality in Dominica.Royer made the remarks during the official launching of a three month training workshop for the management of Diabetic Foot in Dominica this morning.She says statistics indicate that diabetes is the third cause of both morbidity and mortality in Dominica and has proven to be very costly to individuals, families and the country.According to Royer, the increase of amputation related to diabetes is of major concern for the Ministry of Health and it is against this background that the diabetic foot care program was initiated since experts remain convinced that the majority of many amputations can be avoided.She told the ceremony that not only do these patients suffer from the amputation of their limbs, but also a significant psychological impact which can be very severe.“Amputation does not only result in loss of mobility but can have a considerable psychological impact on the entire family. In fact many people who have had amputations report feeling emotions such as grief and bereavement similar to experiencing the death of a loved one.”She explained that it was with this in mind that the training workshop was established with a view to exploring methods in which amputations could be prevented.“The workshop offers a concentrated program on how to treat and assess advanced lower extremities, arterial disease with the goal of saving the limb. The training brings together experienced skilled professionals who will provide specific detailed information about proper diagnosis and management and will give physicians the knowledge to make critical decisions that will ensure the best possible outcome for every patient they come in contact with at the community or hospital setting.”At the end of the workshop, participants are expected to be further inspired and equipped to effectively execute their role in the prevention of amputation.It is also hoped that the training will be an impetus to continue to avail new opportunities for addressing the issue of diabetes and amputation.Dominica Vibes Newslast_img read more

Regional Testing Day: 27th June, 2011

first_img 6 Views   no discussions Tweet LocalNews Regional Testing Day: 27th June, 2011 by: – June 23, 2011 Sharing is caring! Photo credit: health.unl.eduRegional Testing Day, a partnership between the Caribbean Broadcast Media Partnership on HIV and AIDS and Scotia bank, will be observed this year on June 27th.Expanded from its pilot programme in 2008, which was concentrated in Barbados, the initiative aims, this year, to have approximately 10,000 people across the region tested.One of the main reasons for this testing campaign is to encourage everyone to know his/her status, since knowing ones’ HIV status is better than not knowing.To fulfill the mandate of Regional Testing Day, Dominica’s National HIV and AIDS Response Programme will provide testing on June 24th and 25th. Testing will be done in all health districts on the 24th and in the Carib Territory on the 25th.Press Releasecenter_img Share Share Sharelast_img read more

Dominica wins Courts OECS reading competition

first_img Share Sharing is caring! EducationLocalNewsPrimary Dominica wins Courts OECS reading competition by: – October 21, 2011 Share Tweetcenter_img Shania Edwards and her mother after she won the competition in Dominica earlier this year.Shania Edwards, a student of the Massacre Primary has read her way to winning the 2011 Courts OECS reading competition which took place in St Kitts on Thursday.Principal of the Massacre Primary Cynthia Morvan told DBS News that the victory is a proud moment for everyone who made it possible.“We listened to her from the beginning and when she did the first round we knew she had made it. We had no doubt that she would be the winner. When it was announced we were excited. We are happy for her and her family. Right now the entire school is on top of the world. It tells us that every child can read and we can do it. I want to appeal to the parents to stand by their parents because what we realize is that when parents work with their children, they do well. Shania has a good family support and she has a good attitude, which is one of the beautiful things about Shernia,” she said Marketing Officer of Courts Letricia Cadette says the organization is elated at the results.“We are excited. It was a fun filled day. It has been interesting as well. She read at number 5. She was brilliant,” she said.St Kitts placed second while St Lucia placed third.The event is the brainchild of the Dominica Broadcasting Station.A welcome ceremony will be held at the Melville Hall Airport to welcome Edwards.Dominica Vibes News 80 Views   2 comments Sharelast_img read more

Three more Grenada police officers charged in beating death

first_img Share Flag of Grenada. Photo credit: mapsofworld.comST GEORGE’S, Grenada — Three more Royal Grenada Police Force officers were charged with manslaughter on Sunday in the death of a Grenadian-born Canadian resident Oscar Bartholomew.Edward Gibson, Shaun Ganness and Ruddy Felix had been detained in custody since Friday before being charged.Two other police officers, Kenton Hazzard and Wendell Sylvester, were earlier charged with manslaughter on Saturday.All five police officers are due to appear in court on Tuesday.According to the Bartholomew family’s lawyer, more charges could be brought, as witness accounts indicate as many as eight officers might have been involved.Bartholomew, 39, who is originally from Grenada but a permanent resident of Canada, had returned to his homeland for an annual family visit. He died last Tuesday, after allegedly being beaten by a group of police officers.The incident may have resulted from a case of mistaken identity outside the police station in St David’s, when Bartholomew is said to have mistaken a plainclothed police officer for an old family friend and didn’t realize the mistake until after he ran over, hugged and lifted the woman off the ground.Although Bartholomew reportedly put the woman down after realizing his mistake, other plainclothed officers considered it an assault on an officer, and took Bartholomew inside the police station. While in custody, Bartholomew was allegedly beaten and later died in hospital of his injuries. His death certificate gives the cause of death as head trauma, including internal bleeding and skull fractures.The incident has caused a national and international uproar. By Caribbean News Now contributor Share 14 Views   no discussions Sharecenter_img Sharing is caring! NewsRegional Three more Grenada police officers charged in beating death by: – January 3, 2012 Tweetlast_img read more

Four presumed dead in emergency flight crash.

first_img Share Share Tweet NewsRegional Four presumed dead in emergency flight crash. by: – May 8, 2012 Sharing is caring!center_img Share 60 Views   no discussions plane_news.caribseek.comMARIGOT, St Martin – A medical emergency flight crashed shortly after departing L’Éspérance Airport in Grand Case early Saturday morning, presumably killing all four aboard: a honeymooning cruise ship passenger from Cyprus who suffered heart trouble, a nurse, a doctor and the pilot.The plane was carrying the patient identified as Panagiotis Vryonides of Nicosia, Cyprus, around 30 years old, to Martinique for specialised cardiac care.The doctor was identified as Jean-Michel Dudouit and the nurse as Gerard Omere, both of Pierre Zobda Quitman University Hospital Centre in Fort-de-France. The pilot of the ill-fated air ambulance has been identified as Bruno Le Jeune.According to the Associated Press (AP), a diplomat from Cyprus’ embassy in Washington D.C. will travel to Martinique, where Vryonides’ wife is located, to offer support.The Piper Cheyenne III, owned by Transports Aériens Intercaraïbes (TAI), crashed four minutes after takeoff from L’Éspérance Airport. The AP reported that Martinique officials had said they originally had sent another plane that experienced mechanical problems on arriving at Princess Juliana International Airport in St. Maarten and it had been replaced by the plane that crashed.Préfet Délégué Phillipe Chopin said French Civil Aviation representatives had arrived in St. Martin on Sunday to begin the investigation into the cause of the accident. He also has issued orders preventing travel to Tintamarre to safeguard debris/evidence from trophy seekers.The Préfet also is dealing with reports that the aircraft was not suitable to execute medivacs, considering a decision taken by his predecessor to disallow the transport of patients from Louis Constant Fleming Hospital using the aircraft in question. Reportedly TAI only transports patients who pay for private air evacuation.Emergency search operations are being executed by Dutch and French authorities. According to St. Maarten Sea Rescue Foundation, which took part in the search operations, debris found consisted not only of material debris from the airplane, but also what appeared to be human remains were taken aboard the rescue vessels and later handed over to the French authorities.The two Sea Rescue Foundation vessels, Rescue 01 and Rescue 02, were accompanied by the French rescue boat SNS 129 and quickly determined a search pattern that led them toward St. Barths.The two-man crew on Recue 01 talked to some local fishermen who were out as well, but they reportedly did not see anything that could help in finding the direction in which the plane was going.“At daybreak a French authority’s rescue helicopter found some debris between St. Maarten and Tintamarre Island,” a release from the Sea Rescue Foundation read. “The rescue crew then knew what direction the debris was going in and went there to assist the French Gendarmes and Customs that were also looking for survivors. A Dutch Caribbean Coast Guard airplane also joined the search and went on looking for survivors or any other leads to the fate of the airplane.“Most of the small debris particles were found in a trail of seaweed floating close to Tintamarre Island and the rescue vessels had to proceed with caution to try and pick up the debris without causing more damage for research purposes. Quickly it was learned that the debris found did not only consist of material debris from the airplane, but remains that appeared to be human were also taken aboard the Rescue vessels and later handed to the French authorities.”The Sea Rescue Foundation added that a French military helicopter that also joined the search operation had found large debris on the ocean floor around 8:00am Saturday and the French authorities had gone to the location with divers, assisted by the three rescue vessels.“The search continued for some time, hoping to still find survivors, but was eventually called off by the Rescue Coordination centre,” the Sea Rescue Foundation said.Carib Seek Newslast_img read more